Clarke County is a county located in the U.S. state of Mississippi. As of the 2010 census, the population was 16,732. Its county seat is Quitman. Clarke County is named for Joshua G. Clarke, the first Mississippi state chancellor and judge.The county is part of the Meridian, MS Micropolitan Statistical Area.GeographyAccording to the U.S. Census Bureau, the county has a total area of, of which is land and (0.3%) is water.Major highways20px Interstate 5920px U.S. Highway 1120px U.S. Highway 4520px Mississippi Highway 18Adjacent countiesLauderdale County (north)Choctaw County, Alabama (east)Wayne County (south)Jasper County (west)
