Grady County is a county located in the U.S. state of Oklahoma. As of the 2010 census, the population was 52,431. Its county seat is Chickasha. It was named for Henry W. Grady, an editor of the Atlanta Constitution and southern orator.Grady County is part of the Oklahoma City, OK Metropolitan Statistical Area.HistoryGrady County was part of the land given to the Choctaw by the Treaty of Dancing Rabbit Creek, in exchange for property in the southeastern United States. In 1837, the Chickasaw joined the Choctaws, and in 1855 a treaty separated the two tribes, and the Chickasaw acquired an area that included much of Grady County. Most of the present Grady County became a part of Pickens County in the Chickasaw Nation.Before the Civil War, Randolph B. Marcy blazed the California Road through this area, reporting a Waco and a Wichita village. In 1858, while the Comanches were holding a meeting with the Wichita, Choctaw, and Chickasaw, Federal troops attacked a party of Comanches. Although the commander of Fort Arbuckle had been informed about the meeting, the troops' commander, Major Earl Van Dorn, had not consulted him before the attack. As a result, the troops killed 60 Comanches and four Wichitas. Fearing a Comanche reprisal, the other tribes fled to safety at Fort Arbuckle. At the end of the Civil War, the Five Civilized Tribes and the Caddo, Delaware, Kiowa, Comanche, Apache, Cheyenne, Arapaho, and Osage signed a peace agreement and pledged to stand united against any unjust demands that the federal government made at the war's end. The agreement was known as the Camp Napoleon Compact.