Greenwood is a city in and the county seat of Greenwood County, South Carolina, United States. The population was 23,222 at the 2010 census. The city is home to Lander University.GeographyGreenwood is located slightly northwest of the center of Greenwood County. According to the United States Census Bureau, the city has a total area of 42.3km2, of which 42.0km2 are land and 0.3sqkm, or 0.72%, are water.U.S. Routes 25, 178 and 221 pass through the eastern side of the city, bypassing the downtown area. US 25 leads north to Greenville and south to Augusta, Georgia, US 178 leads northwest to Anderson and southeast to Saluda, and US 221 leads northeast to Laurens and southwest to McCormick.Lake Greenwood, a reservoir on the Saluda River, is 8mi northeast of the city at its nearest point. The lake has of shoreline, covers, and is almost long. Lake Greenwood State Park, built in the 1930s by the Civilian Conservation Corps, is east of the city on the south shore of Lake Greenwood and includes two boat ramps, a campground, trail and playgrounds, and many picnic areas. The area around Greenwood is locally billed as the "Lakelands", due to several lakes for recreational fishing and diverse terrain for hiking trails.