Holly Hill is a town in Orangeburg County, South Carolina, United States. The population was 1,281 at the 2000 census. Prior to 1910 it was located in the northwest portion of Saint James Goose Creek Township, Berkeley County.HistoryDantzler Plantation and Providence Methodist Church are listed on the National Register of Historic Places.GeographyHolly Hill is located at .According to the United States Census Bureau, the town has a total area of 1.4sqmi, all of it land.DemographicsAs of the census of 2000, there were 1,281 people, 502 households, and 359 families residing in the town. The population density was 950.7 people per square mile (366.4/km²). There were 575 housing units at an average density of 426.7 per square mile (164.5/km²). The racial makeup of the town was 48.95% White, 50.04% African American, 0.39% Native American, 0.08% Asian, and 0.55% from two or more races. Hispanic or Latino of any race were 0.47% of the population.There were 502 households out of which 27.9% had children under the age of 18 living with them, 50.6% were married couples living together, 18.9% had a female householder with no husband present, and 28.3% were non-families. 26.5% of all households were made up of individuals and 13.9% had someone living alone who was 65 years of age or older. The average household size was 2.53 and the average family size was 3.05.