Jamestown is a borough in Mercer County, Pennsylvania, United States, along the Shenango River. The population was 636 at the 2000 census. It is part of the Youngstown-Warren-Boardman, OH-PA Metropolitan Statistical Area.HistoryThe town was founded in 1798 by James Campbell. The borough was incorporated in 1853.The Jamestown area is served by the Jamestown Area School District, and is home to Combined Systems Inc, a tactical weapons producer that exports tear gas and smoke grenades.The Gibson House was added to the National Register of Historic Places in 1978.GeographyJamestown is located at .According to the United States Census Bureau, the borough has a total area of 0.8sqmi, of which, 0.8sqmi of it is land and 1.27% is water.DemographicsAs of the census of 2000, there were 636 people, 269 households, and 171 families residing in the borough. The population density was 819.5 people per square mile (314.8/km2). There were 297 housing units at an average density of 382.7 per square mile (147.0/km2). The racial makeup of the borough was 99.53% White, and 0.47% from two or more races.