Joseph C. Ferguson School is a historic school building located in the Templetown neighborhood of Philadelphia, Pennsylvania. It was designed by Irwin T. Catharine and built in 1921-1922. It is a three-story, nine bay, "U"-shaped, brick building on a raised basement in the Colonial Revival-style. It features large stone arches, a double stone cornice, and brick parapet.It was added to the National Register of Historic Places in 1988.The building is currently the home of Building 21 and the U School, two innovative high schools in the School District of Philadelphia. They opened during the 2014–2015 school year and have a non-selective lottery-based admissions process.