Mauldin is a city in Greenville County, South Carolina, United States. The population was 15,224 at the 2000 census, 22,889 in 2010, and an estimated 25,135 in 2015. It is a principal city of the Greenville-Anderson-Mauldin Metropolitan Statistical Area.GeographyMauldin is located south of the center of Greenville County, between the city of Greenville to the northwest and Simpsonville to the southeast. According to the United States Census Bureau, the city has a total area of 25.9km2, of which 0.1sqkm, or 0.46%, are water.U.S. Route 276 (Main Street) passes through the center of Mauldin, leading northwest 8mi to the center of Greenville and southeast 5mi to Simpsonville. Interstate 385 runs through the eastern side of Mauldin, leading north to Interstate 85 on the east side of Greenville. I-385 connects with Interstate 185 on the southern edge of Mauldin, and I-185 continues west and northwest to join I-85 on the southwest side of Greenville. From its interchange with I-185, I-385 leads southeast to Interstate 26 near Clinton.
