The Mississippi County Courthouse for the Chickasawba District is located at 200 West Walnut Street in Blytheville, Arkansas, one of Mississippi County's two seats (the other is Osceola). It is a 3-1/2 story brick and cut sandstone structure, designed by the Pine Bluff firm of Selligman and Ellesvard, and built in 1919. It is a fine local example of Colonial Revival styling, with a recessed center entrance and a projecting modillioned cornice. The interior has been little altered since its construction.The building was listed on the National Register of Historic Places in 1996.