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Wayne County, NY Founded in 1823, is located in the Finger Lakes Region of New York State. The County is part of the Rochester, NY Metropolitan Statistical Area and lies on the south shore of Lake Ontario, forming part of the northern border of the United States with Canada. In addition, the historic Erie Canal transits the southern edge of the county. Wayne County’s key industries employ nearly 50,000 people and include advanced manufacturing, agriculture, and photonics, optics, and imaging.