Waynesboro is a city in and the county seat of Wayne County, Tennessee, United States. The population was 2,449 at the 2010 census, up from 2,228 in 2000.HistoryWaynesboro was founded in 1821 as a county seat for the newly created Wayne County. The city initially consisted of a 40acre plot that included the courthouse and jail. A school, Ashland Academy, was established in 1843. The city incorporated in 1850.GeographyWaynesboro is located at . The city is concentrated around the junction of State Route 13 and U.S. Route 64, 105mi south of Nashville, and 135mi east Memphis. State Route 99, which intersects US 64 in eastern Waynesboro, connects the city with Hohenwald to the northeast. The Natchez Trace Parkway intersects US 64 a few miles east of Waynesboro.Waynesboro lies along the banks of the Green River, which slices a narrow valley oriented north-to-south en route to its mouth along the Buffalo River to the north. Hurricane Creek, which approaches from the southeast, empties into the Green River just north of the city. Much of the forest northwest of Waynesboro is part of the Eagle Creek Wildlife Management Area.
