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Reviews, get directions and information for Zymology 21

Zymology 21

About

Zymology 21 is a lounge & eatery serving brunch, dinner & late night cocktails. Our "lab" features molecular mixology from Chef Leyla of Cafe 21 fame.

Description

Zymology 21, the newest restaurant and bar concept to hit downtown San Diego, is the third concept from the C21 Restaurant Group, known for the award-winning Café 21 restaurants in University Heights and the Gaslamp Quarter. Serving brunch, dinner and late night cocktails daily, the menu features specialty food items and inventive farm-to-bar cocktails from chef Leyla Javadov’s “laboratory” that are formulated using house fermentation, puree and infusion techniques.

Zymology 21 is elevating what has become the typical Gaslamp nightlife experience by taking guests on a taste experiment that ignites all of the senses. One that mixes the old processes of “zymology,” a scientific field that studies fermentation, with modern cocktail preparations that include molecular mixology.

Address: 750 5th Ave, San Diego 92101
Phone: (619) 546-9321
Parking: Lot, Street, Valet
State: CA
City: San Diego
Street Number: 750 5th Ave
Zip Code: 92101
categories: pub, restaurant


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Reviews
The service was fantastic. They were out of my wife's initial order Ahi Tuna Sliders, so they covered the cost of her dinner and our drinks we each had a beer. It's open seating and the servers were prompt. The Chicken and Waffles were excellent and you get pretty generous portions for the price. Solid beer selection. I didn't try any of the cocktails but they looked really creative.
I'd love to give this place a better review because I like the concept, but execution was definitely off during our visit. We rolled in during a Friday Happy Hour, relatively quiet, only a couple at the bar, and 2 tables filled. Asked about Happy Hour specials and was show a 1 page menu along with the regular menu. It was confusing to understand how the mix and matches work between the "scrub", the liquors, and the mixed drinks. I ordered a mule, which was average at best. My wife ordered a 'shrub' cocktail which turned out quite well. Around us we saw liquid fire turning into dry ice as a cool piece of showmanship ordered by another table. This is why I've gone with two stars... 1 disengaged bartender, busy cleaning than helping the customer 2 mules were not very good 3 TURNS OUT MORE WAS ON HAPPY HOUR - we got the bill and my wife's drink was $7 vs $10 on the menu. I ordered a $5 mule as $10 seemed steep - If i knew those drinks were on sale, I would have ordered one! As another reviewer wrote, so much potential, but poorly executed by fixable operations and service.
This place is fun and hip and where you wanna be if you like unique, hand crafted and strong cocktails! Are you a science geek or do you just love a good mix and mingle! Well Zymology is right up your alley! Was here for a special event and I have to say I was impressed. Did not try the food although I am curious and believe me if you plan on ordering some of their cocktails please please please order food with it! They do not play around, these brews pack a punch!!! The mixes are unique and well thought out and I loved all the science behind it all since I was going to be a Bio major before I became a college drop out for beauty school! But, with all seriousness I truly loved their approach and this is a not a place for the light weight but, definitely a unique establishment to check out while in downtown San Diego!
Cute and well-themed. Sister/brother whichever company to Cafe 21 you guys did it again! The oh so cute company is well themed and quite clever. At Zymology you get the feel that you are at lab drinking from beakers, mixing glasses, and the like. They also add mist to seem as if the drinks are brewing. Good place to go with friends and to enjoy drinks. I definitely did. I had the champagne popsicle and it was delicious. Not strong but a cute girly drink. We also had the margarita flight and boy were those strong. A good strong. Visited during the busy labor day weekend the first week they opened so service was quite slow and it seemed only one guy veteran cafe 21 employee knew what the deal was but he sure did deliver. Great service from him and makes you want to visit again. Sadly did not get to try their food but will be making a separate trip for that as their menu boasted some very interesting items. Place definitely has potential to keep busy during the weekend.
Great cocktail spot and solid food options. On a recent visit had the mule which was perfect for a hot SD summer afternoon. Also ordered the cuban sandwich, which is an open faced version of the traditional cuban sandwich. Bartenders are very friendly and knowledgeable. Service is great. Can't wait to go back and try the brunch menu!
Service is obviously incredible, shouldn't even be a question. The atmosphere and camaraderie they create incredible. Every moment of the experience feels interactive and everyone in the restaurant feels connected. The drinks are delicious and interesting. Order the test tube flight or some tea if you want a show.
My fiance and found this place on a whim when walking by. So happy we did, Service -awesome and extremely friendly,-Shrub drinks refreshing and the chicken and waffles. . Delicious
Always lively staff, friendly, and creative menus make this a staple whenever I'm in San Diego especially the Comic Con. Do yourself the favor, i promise you won't regret it!
If you are feeling adventurous and wanting to experience something out of the ordinary then this is the place for you. Very fun and lively service with tasty food/drink to match.
Amazing food and even better drinks with the way they craft them and break it down. The most unique restaurant/bar in San Diego.
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