Chamberlain is a city in Brule County, South Dakota, United States. It is located on the Eastern bank of the Lake Francis Case dammed section of the Missouri river, close to where it is crossed by Interstate 90 highway.The population of Chamberlain was 2,387 at the 2010 census. It is the county seat of Brule County.Chamberlain is home to the Saint Joseph's Indian School, which also includes the Akta Lakota Museum and Cultural Center, which profiles the lives of nomadic Plains Indians. Chamberlain is the home of the South Dakota Hall of Fame, and the 50-foot statue of a Native American woman, Dignity, stands nearby.HistoryChamberlain was named after Selah Chamberlain, a railroad director of the Chicago, Milwaukee and St. Paul Railway.GeographyChamberlain is located at .According to the United States Census Bureau, the city has a total area of 7.84sqmi, of which, 6.64sqmi is land and 1.20sqmi is water.Chamberlain has been assigned the ZIP code range 57325-57326 and the FIPS place code 11220.
