Denison House, also known as the Colonel Nathan Denison House, is a historic home located at Forty Fort, Luzerne County, Pennsylvania. It was built about 1790, and is a 2 1/2-story, frame building with a central chimney in the New England style. A rear addition and full-width front porch were added in the mid-19th century.It was added to the National Register of Historic Places in 1970.