Denison is a city in Grayson County, Texas, United States. It is north of Dallas. The population was 22,682 at the 2010 census. Denison is part of the Texoma region and is one of two principal cities in the Sherman–Denison Metropolitan Statistical Area. Denision is known as the birthplace of Dwight D. Eisenhower, the 34th President of the United States.HistoryDenison was founded in 1872 in conjunction with the Missouri–Kansas–Texas Railroad (MKT) or "Katy" depot. It was named after the wealthy Katy vice president George Denison. Because the town was established close to where the MKT crossed the Red River (both important conduits of transportation in the industrial era), it came to be an important commercial center in the 19th century American West. In 1875, Doc Holliday had offices in Denison.During the phylloxera epidemic of the mid-19th century, which destroyed the vast majority of wine grapes in Europe, Denison horticulturalist T.V. Munson pioneered methods in creating phylloxera-resistant vines, and earned induction into the French Legion of Honor, as well as sister city status for Denison and Cognac, France.