Otay Mesa is a community in the southern section of the city of San Diego, just north of the U.S.–Mexico border.It is bordered by the Otay River Valley and the city of Chula Vista on the north; Interstate 805 and the neighborhoods of Ocean View Hills and San Ysidro on the west; unincorporated San Diego County on the north and east including East Otay Mesa and the San Ysidro Mountains; and the Otay Centenario borough of Tijuana Municipality, Mexico on the south.Major thoroughfares include Otay Mesa Road/California State Route 905, Otay Valley Road/Heritage Road, Siempre Viva Road, and California State Route 125. Otay Mesa is the second-least walkable neighborhood of San Diego.HistoryOtay is derived from the Kumeyaay language. Although its meaning is disputed, possible derivations include "otai", meaning "brushy"; "Tou-ti" meaning "big mountain"; or "etaay" meaning "big". Mesa is the Spanish word for plateau, table or tableland.
