Treadwell Street Historic District is a national historic district located at Orangeburg, Orangeburg County, South Carolina. The district encompasses 39 contributing buildings in an African American residential section of Orangeburg. They include one-story, weatherboard frame dwellings dated between about 1890 and 1930. The houses are in a variety of popular architectural styles including Victorian and Bungalow.It was added to the National Register of Historic Places in 1985.
