Horn Lake is a city in DeSoto County, Mississippi, United States which is located south of Memphis, Tennessee. As of the 2010 U.S. Census, the population of Horn Lake was 26,066, up from 14,099 in 2000.GeographyHorn Lake is bordered to the north, east, and southeast by the city of Southaven. U.S. Route 51 forms a large portion of Horn Lake's eastern border; it leads north to downtown Memphis, and south 9mi to Hernando, the DeSoto County seat. Interstate 55 passes just east of Horn Lake, with access from Exits 287 and 289.According to the United States Census Bureau, the city of Horn Lake has an area of 42.3km2, of which 41.5sqkm is land and 0.8sqkm, or 1.98%, is water.EconomyHorn Lake is the site of a plant owned by Chicago-based Newly Weds Foods, which manufactures food coatings, seasonings, and other ingredients for the food processing and service industries.The headquarters of the American Contract Bridge League are in Horn Lake, along with a related Hall of Fame, museum, and library.The "Elvis Ranch", a 154.5acre ranch owned by Elvis Presley during the last decade of his life, is in Horn Lake.EducationHorn Lake is served by the DeSoto County School District.