Ashtabula is a plantation house at 2725 Old Greenville Highway near Pendleton in Anderson County, South Carolina, USA. It has been also known as the Gibbes-Broyles-Latta-Pelzer House or some combination of one or more of these names. It was named in the National Register of Historic Places as a historic district on March 23, 1972. It is considered a significant example of a Lowcountry style plantation house built for a Charleston family in the Upstate in the early 19th century. It also is part of the Pendleton Historic District.HistoryAround 1790, Thomas Lofton built a two-story, brick house at the site. Later, the Gassaway family owned the house, which they operated as a tavern on the stage road from Pendleton to Pickensville and Greenville.In the mid-1820s, Lewis Ladson Gibbes from Charleston built the frame house now known as Ashtabula. His spouse was Maria Drayton of Drayton Hall and a niece of Arthur Middleton. She died in 1826 and he died in 1828 just before the completion of the house. Some of their children lived in the house.